Overexpression of filamin c in chronic intermittent hypoxia-induced cardiomyocyte apoptosis is a potential cardioprotective target for obstructive sleep apnea.

Yang, Xuechao; Shi, Yang; Zhang, Linfei; Liu, Huan; Shao, Yongfeng; Zhang, Shijiang

Yang, Xuechao; Shi, Yang; Zhang, Linfei; Liu, Huan; Shao, Yongfeng; Zhang, Shijiang.

Afiliação

Yang X; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, Jiangsu, People's Republic of China.
Shi Y; Department of Cardiothoracic Surgery, Yancheng First People's Hospital, Yancheng, 224001, Jiangsu, People's Republic of China.
Zhang L; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, Jiangsu, People's Republic of China.
Liu H; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, Jiangsu, People's Republic of China.
Shao Y; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, Jiangsu, People's Republic of China.
Zhang S; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, Jiangsu, People's Republic of China. shijiangzhang@hotmail.com.

Sleep Breath ; 23(2): 493-502, 2019 Jun.

Article em En | MEDLINE | ID: mdl-30194514

Assuntos

Apoptose/genética; Cardiotônicos; Filaminas/genética; Regulação da Expressão Gênica/genética; Hipóxia/genética; Miócitos Cardíacos/metabolismo; Apneia Obstrutiva do Sono/genética; Animais; Correlação de Dados; Imunofluorescência; Miócitos Cardíacos/patologia; Ratos; Ratos Sprague-Dawley; Apneia Obstrutiva do Sono/patologia

Palavras-chave

Cardiomyocyte apoptosis; Chronic intermittent hypoxia; FLNC; Obstructive sleep apnea

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiotônicos / Regulação da Expressão Gênica / Apoptose / Apneia Obstrutiva do Sono / Miócitos Cardíacos / Filaminas / Hipóxia Limite: Animals Idioma: En Revista: Sleep Breath Assunto da revista: NEUROLOGIA / OTORRINOLARINGOLOGIA Ano de publicação: 2019 Tipo de documento: Article

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