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Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target.
Yángüez, Emilio; Hunziker, Annika; Dobay, Maria Pamela; Yildiz, Soner; Schading, Simon; Elshina, Elizaveta; Karakus, Umut; Gehrig, Peter; Grossmann, Jonas; Dijkman, Ronald; Schmolke, Mirco; Stertz, Silke.
Afiliação
  • Yángüez E; Institute of Medical Virology, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Hunziker A; Institute of Medical Virology, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Dobay MP; Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, Quartier Sorge-Batiment Genopode, Lausanne, 1015, Switzerland.
  • Yildiz S; Department of Microbiology and Molecular Medicine, University of Geneva, Rue Michel-Servet 1, CH-1211, Geneva, Switzerland.
  • Schading S; Institute of Medical Virology, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Elshina E; Institute of Medical Virology, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Karakus U; Institute of Medical Virology, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Gehrig P; Functional Genomics Centre Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Grossmann J; Functional Genomics Centre Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
  • Dijkman R; Institute of Virology and Immunology, Länggassstrasse 122, 3012, Bern, Switzerland.
  • Schmolke M; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
  • Stertz S; Department of Microbiology and Molecular Medicine, University of Geneva, Rue Michel-Servet 1, CH-1211, Geneva, Switzerland.
Nat Commun ; 9(1): 3679, 2018 09 11.
Article em En | MEDLINE | ID: mdl-30206219

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Fosfoproteínas / Proteínas Quinases / Proteômica / Influenza Humana / Quinase 2 de Receptor Acoplado a Proteína G / Terapia de Alvo Molecular Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Fosfoproteínas / Proteínas Quinases / Proteômica / Influenza Humana / Quinase 2 de Receptor Acoplado a Proteína G / Terapia de Alvo Molecular Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça