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Identification of a cellularly active SIRT6 allosteric activator.
Huang, Zhimin; Zhao, Junxing; Deng, Wei; Chen, Yingyi; Shang, Jialin; Song, Kun; Zhang, Lu; Wang, Chengxiang; Lu, Shaoyong; Yang, Xiuyan; He, Bin; Min, Jinrong; Hu, Hao; Tan, Minjia; Xu, Jianrong; Zhang, Qiufen; Zhong, Jie; Sun, Xiaoxiang; Mao, Zhiyong; Lin, Houwen; Xiao, Mingzhe; Chin, Y Eugene; Jiang, Hualiang; Xu, Ying; Chen, Guoqiang; Zhang, Jian.
Afiliação
  • Huang Z; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Zhao J; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Deng W; Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Chen Y; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Shang J; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Song K; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Zhang L; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Wang C; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Lu S; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Yang X; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • He B; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guizhou Medical University, Guiyang, China.
  • Min J; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.
  • Hu H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Tan M; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Xu J; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Zhang Q; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Zhong J; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
  • Sun X; School of Life Sciences and Technology, Tongji University, Shanghai, China.
  • Mao Z; School of Life Sciences and Technology, Tongji University, Shanghai, China.
  • Lin H; Basic Clinical Research Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Xiao M; Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Chin YE; Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Jiang H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Xu Y; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. yingxuxu@shsmu.edu.cn.
  • Chen G; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. chengq@shsmu.edu.cn.
  • Zhang J; Key Laboratory of Cell Differentiation and Apoptosis, Ministry of Education, Department of Pathophysiology, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. jian.zhang@sjtu.edu.cn.
Nat Chem Biol ; 14(12): 1118-1126, 2018 12.
Article em En | MEDLINE | ID: mdl-30374165
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Enxofre / Benzoatos / Sirtuínas / Ensaios de Triagem em Larga Escala / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Enxofre / Benzoatos / Sirtuínas / Ensaios de Triagem em Larga Escala / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China