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Antiplatelet therapy in patients undergoing oral surgery: A systematic review and meta-analysis.
Villanueva, J; Salazar, J; Alarcón, A; Araya, I; Yanine, N; Domancic, S; Carrasco-Labra, A.
Afiliação
  • Villanueva J; Sergio Livingstone P 943, Independencia, Santiago de Chile, javm@uchile.cl.
Med Oral Patol Oral Cir Bucal ; 24(1): e103-e113, 2019 Jan 01.
Article em En | MEDLINE | ID: mdl-30573718
BACKGROUND: The number of patients under antiplatelet therapy (APT) continues to raise as current recommendations foster this practice. Although some recommendations to manage this treatment during oral surgery procedures exist, these have methodological shortcomings that preclude them from being conclusive. MATERIAL AND METHODS: A systematic review and meta-analysis of the best current evidence was carried out; The Cochrane Library, EMBASE and MEDLINE databases were searched for Randomized Controlled Trials (RCT) concerning patients undergoing oral surgery with APT, other relevant sources were searched manually. RESULTS: 5 RCTs met the Inclusion criteria. No clear tendency was observed (RR= 0.97 CI 95%: 0,41-2,34; p=0,09; I2= 51%), moreover, they weren't clinically significant. CONCLUSIONS: According to these findings and as bleeding is a manageable complication it seems unreasonable to undermine the APT, putting the patient in danger of a thrombotic event and its high inherent morbidity, which isn't comparable in severity and manageability to the former."
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Agregação Plaquetária / Procedimentos Cirúrgicos Bucais Tipo de estudo: Clinical_trials / Guideline / Systematic_reviews Limite: Humans Idioma: En Revista: Med Oral Patol Oral Cir Bucal Assunto da revista: ODONTOLOGIA Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Agregação Plaquetária / Procedimentos Cirúrgicos Bucais Tipo de estudo: Clinical_trials / Guideline / Systematic_reviews Limite: Humans Idioma: En Revista: Med Oral Patol Oral Cir Bucal Assunto da revista: ODONTOLOGIA Ano de publicação: 2019 Tipo de documento: Article