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Chemical Imaging in Vivo: Photoacoustic-Based 4-Dimensional Chemical Analysis.
Lee, Chang H; Folz, Jeff; Tan, Joel W Y; Jo, Janggun; Wang, Xueding; Kopelman, Raoul.
Afiliação
  • Lee CH; Department of Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Folz J; Biophysics Program , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Tan JWY; Department of Biomedical Engineering , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Jo J; Department of Biomedical Engineering , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Wang X; Department of Biomedical Engineering , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Kopelman R; Department of Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States.
Anal Chem ; 91(4): 2561-2569, 2019 02 19.
Article em En | MEDLINE | ID: mdl-30638359
ABSTRACT
We describe how 4-dimensional in vivo biochemical analysis can be performed using photoacoustic contrast nanoagents that have been designed to probe both structural and chemical information in vivo, enabling noninvasive, real time, spatially resolved chemical imaging. Early chemical imaging of a patient's tumor can inform the decision of effective treatment, regarding choices of chemotherapy, radiation, or immunotherapy.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas de Química Analítica / Técnicas Fotoacústicas / Neoplasias Limite: Animals / Humans Idioma: En Revista: Anal Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas de Química Analítica / Técnicas Fotoacústicas / Neoplasias Limite: Animals / Humans Idioma: En Revista: Anal Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos