Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation.

Eriksson, Oskar; Chiu, Joyce; Hogg, Philip J; Atkinson, John P; Liszewski, M Kathryn; Flaumenhaft, Robert; Furie, Bruce

Eriksson, Oskar; Chiu, Joyce; Hogg, Philip J; Atkinson, John P; Liszewski, M Kathryn; Flaumenhaft, Robert; Furie, Bruce.

Afiliação

Eriksson O; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.
Chiu J; the Centenary Institute, National Health and Medical Research Council Clinical Trials Centre, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia, and.
Hogg PJ; the Centenary Institute, National Health and Medical Research Council Clinical Trials Centre, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia, and.
Atkinson JP; the Department of Medicine/Rheumatology, Washington University School of Medicine, St. Louis, Missouri 63110.
Liszewski MK; the Department of Medicine/Rheumatology, Washington University School of Medicine, St. Louis, Missouri 63110.
Flaumenhaft R; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.
Furie B; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115, bfurie@bidmc.harvard.edu.

J Biol Chem ; 294(13): 4878-4888, 2019 03 29.

Article em En | MEDLINE | ID: mdl-30670593

Assuntos

Lectina de Ligação a Manose da Via do Complemento; Glicoproteínas/metabolismo; Lectinas/metabolismo; Isomerases de Dissulfetos de Proteínas/metabolismo; Multimerização Proteica; Proteólise; Glicoproteínas/genética; Humanos; Lectinas/genética; Isomerases de Dissulfetos de Proteínas/genética

Palavras-chave

ER protein 57 (ERp57); complement system; disulfide; ficolin; innate immunity; lectin pathway; mass spectrometry (MS); redox regulation; thiol isomerase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Isomerases de Dissulfetos de Proteínas / Lectina de Ligação a Manose da Via do Complemento / Multimerização Proteica / Proteólise / Lectinas Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article

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