N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation.

Wen, Zhenke; Jin, Ke; Shen, Yi; Yang, Zhen; Li, Yinyin; Wu, Bowen; Tian, Lu; Shoor, Stanford; Roche, Niall E; Goronzy, Jorg J; Weyand, Cornelia M

Wen, Zhenke; Jin, Ke; Shen, Yi; Yang, Zhen; Li, Yinyin; Wu, Bowen; Tian, Lu; Shoor, Stanford; Roche, Niall E; Goronzy, Jorg J; Weyand, Cornelia M.

Afiliação

Wen Z; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Jin K; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Shen Y; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Yang Z; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Li Y; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Wu B; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Tian L; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Shoor S; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Roche NE; Arthritis Center, Stanford Health Care-ValleyCare, Pleasanton, CA, USA.
Goronzy JJ; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
Weyand CM; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA. cweyand@stanford.edu.

Nat Immunol ; 20(3): 313-325, 2019 03.

Article em En | MEDLINE | ID: mdl-30718913

Assuntos

Proteínas Quinases Ativadas por AMP/imunologia; Aciltransferases/imunologia; Artrite Reumatoide/imunologia; Sinovite/imunologia; Proteínas Quinases Ativadas por AMP/genética; Proteínas Quinases Ativadas por AMP/metabolismo; Aciltransferases/genética; Aciltransferases/metabolismo; Adulto; Animais; Artrite Reumatoide/genética; Artrite Reumatoide/metabolismo; Células Cultivadas; Ativação Enzimática/imunologia; Feminino; Humanos; Masculino; Camundongos Endogâmicos NOD; Camundongos Knockout; Camundongos SCID; Pessoa de Meia-Idade; Interferência de RNA; Sinovite/genética; Sinovite/metabolismo; Linfócitos T/imunologia; Linfócitos T/metabolismo; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Sinovite / Aciltransferases / Proteínas Quinases Ativadas por AMP Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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