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Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.
Stancu, Ilie-Cosmin; Cremers, Niels; Vanrusselt, Hannah; Couturier, Julien; Vanoosthuyse, Alexandre; Kessels, Sofie; Lodder, Chritica; Brône, Bert; Huaux, François; Octave, Jean-Noël; Terwel, Dick; Dewachter, Ilse.
Afiliação
  • Stancu IC; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
  • Cremers N; Alzheimer Dementia Group, Institute of Neuroscience, Catholic University of Louvain, 1200, Brussels, Belgium.
  • Vanrusselt H; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
  • Couturier J; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
  • Vanoosthuyse A; Alzheimer Dementia Group, Institute of Neuroscience, Catholic University of Louvain, 1200, Brussels, Belgium.
  • Kessels S; Alzheimer Dementia Group, Institute of Neuroscience, Catholic University of Louvain, 1200, Brussels, Belgium.
  • Lodder C; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
  • Brône B; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
  • Huaux F; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
  • Octave JN; Louvain Center for Toxicology and Applied Pharmacology, Catholic University of Louvain, 1200, Brussels, Belgium.
  • Terwel D; Alzheimer Dementia Group, Institute of Neuroscience, Catholic University of Louvain, 1200, Brussels, Belgium.
  • Dewachter I; Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.
Acta Neuropathol ; 137(4): 599-617, 2019 04.
Article em En | MEDLINE | ID: mdl-30721409
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Proteínas Adaptadoras de Sinalização CARD / Inflamassomos / Doença de Alzheimer / Agregados Proteicos / Proteína 3 que Contém Domínio de Pirina da Família NLR Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Acta Neuropathol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Proteínas Adaptadoras de Sinalização CARD / Inflamassomos / Doença de Alzheimer / Agregados Proteicos / Proteína 3 que Contém Domínio de Pirina da Família NLR Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Acta Neuropathol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica