Interactive effect of Gm and Km allotypes on cellular immune responses to streptococcal cell wall antigen.

Wachsmuth, R R; Pandey, J P; Fedrick, J A; Nishimura, Y; Sasazuki, T

Wachsmuth, R R; Pandey, J P; Fedrick, J A; Nishimura, Y; Sasazuki, T.

Afiliação

Wachsmuth RR; Department of Basic and Clinical Immunology and Microbiology, Medical University of South Carolina, Charleston.

Exp Clin Immunogenet ; 4(3): 163-6, 1987.

Article em En | MEDLINE | ID: mdl-3078724

RESUMO

Serum samples from 121 unrelated, healthy Japanese individuals were typed for several Gm and Km(1) allotypes. Peripheral blood lymphocytes from these subjects were cultured with streptococcal cell wall (SCW) antigen and the incorporation of 3H-thymidine into T lymphoblasts was measured. Log-linear analysis showed a significant interactive effect of Gm1,17;13,16,21 and Km(1) on the cellular immune response to group A SCW antigen.

Assuntos

Imunidade Celular/genética; Alótipos de Imunoglobulina/imunologia; Alótipos Gm de Imunoglobulina/imunologia; Streptococcus pyogenes/imunologia; Adulto; Antígenos de Bactérias/imunologia; Antígenos de Superfície/imunologia; Parede Celular/imunologia; Humanos; Alótipos de Imunoglobulina/genética; Alótipos Gm de Imunoglobulina/genética; Fenótipo

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptococcus pyogenes / Alótipos Gm de Imunoglobulina / Imunidade Celular / Alótipos de Imunoglobulina Limite: Adult / Humans Idioma: En Revista: Exp Clin Immunogenet Assunto da revista: ALERGIA E IMUNOLOGIA / GENETICA Ano de publicação: 1987 Tipo de documento: Article

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