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Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature.
Spitzhorn, Lucas-Sebastian; Megges, Matthias; Wruck, Wasco; Rahman, Md Shaifur; Otte, Jörg; Degistirici, Özer; Meisel, Roland; Sorg, Rüdiger Volker; Oreffo, Richard O C; Adjaye, James.
Afiliação
  • Spitzhorn LS; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Megges M; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Wruck W; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Rahman MS; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Otte J; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Degistirici Ö; Division of Paediatric Stem Cell Therapy, Clinic for Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Meisel R; Division of Paediatric Stem Cell Therapy, Clinic for Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Sorg RV; Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Hospital, Moorenstr, 5, 40225, Düsseldorf, Germany.
  • Oreffo ROC; Bone and Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, University of Southampton, Southampton, SO16 6YD, UK.
  • Adjaye J; Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany. james.adjaye@med.uni-duesseldorf.de.
Stem Cell Res Ther ; 10(1): 100, 2019 03 18.
Article em En | MEDLINE | ID: mdl-30885246
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Antígenos de Diferenciação / Diferenciação Celular / Células-Tronco Pluripotentes Induzidas / Células-Tronco Mesenquimais / Transcriptoma Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Stem Cell Res Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Antígenos de Diferenciação / Diferenciação Celular / Células-Tronco Pluripotentes Induzidas / Células-Tronco Mesenquimais / Transcriptoma Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Stem Cell Res Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha