Light stimulates tyrosine hydroxylase activity and dopamine synthesis in retinal amacrine neurons.
Science
; 202(4370): 901-2, 1978 Nov 24.
Article
em En
| MEDLINE
| ID: mdl-30997
ABSTRACT
Retinal dopamine-containing amacrine neurons are rapidly activated by light, as shown by an increase in the rate of dopamine formation in vivo and a concomitant increase in the activity of tyrosine hydroxylase, measured in vitro with a subsaturating concentration of pteridine cofactor. Activation of tyrosine hydroxylase also occurs when isolated eyes from rats killed in the dark are exposed to a strobe light. Studies of amacrine neurons should provide basic data about the biochemical processing of visual information, as well as the physiological presynaptic regulatory mechanisms of dopamine-containing neurons.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Retina
/
Tirosina 3-Mono-Oxigenase
/
Dopamina
/
Luz
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1978
Tipo de documento:
Article