Perioperative Management of Bleeding and Transfusion for Lung Transplantation.
Semin Cardiothorac Vasc Anesth
; 24(1): 74-83, 2020 Mar.
Article
em En
| MEDLINE
| ID: mdl-31409203
ABSTRACT
Perioperative allogeneic blood product transfusion is common in lung transplantation and has various implications on the short- and long-term outcomes of lung recipients. This review summarizes the effect of transfusion on outcomes including primary graft dysfunction, chronic lung allograft dysfunction, and all-cause mortality. We outline known risk factors for increased transfusion requirement in lung transplantation and present current evidence regarding the effect of hemostatic agents including antifibrinolytics, recombinant factor VII, and prothrombin complex concentrates. Finally, we highlight the roles of point-of-care coagulation testing and goal-directed transfusion strategies in reducing transfusion requirements in lung transplantation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transfusão de Sangue
/
Perda Sanguínea Cirúrgica
/
Transplante de Pulmão
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Semin Cardiothorac Vasc Anesth
Assunto da revista:
ANESTESIOLOGIA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Estados Unidos