Matrix stiffness regulates SMC functions via TGF-ß signaling pathway.

Tian, Baoxiang; Ding, Xili; Song, Yang; Chen, Weicong; Liang, Jiaqi; Yang, Li; Fan, Yubo; Li, Song; Zhou, Yue

Tian, Baoxiang; Ding, Xili; Song, Yang; Chen, Weicong; Liang, Jiaqi; Yang, Li; Fan, Yubo; Li, Song; Zhou, Yue.

Afiliação

Tian B; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Ding X; Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China.
Song Y; 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Chen W; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Liang J; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Yang L; 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing, 400044, China.
Fan Y; Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China.
Li S; Department of Bioengineering and Department of Medicine, University of California, Los Angeles, CA, 90095, USA.
Zhou Y; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China. Electronic address: yzhou2009@sjtu.edu.cn.

Biomaterials ; 221: 119407, 2019 11.

Article em En | MEDLINE | ID: mdl-31442697

Assuntos

Miócitos de Músculo Liso/citologia; Miócitos de Músculo Liso/metabolismo; Fator de Crescimento Transformador beta/metabolismo; Western Blotting; Proteínas de Ligação ao Cálcio/genética; Proteínas de Ligação ao Cálcio/metabolismo; Células Cultivadas; Proteínas do Citoesqueleto/genética; Proteínas do Citoesqueleto/metabolismo; Epirregulina/genética; Epirregulina/metabolismo; Humanos; Imuno-Histoquímica; Metaloproteinase 2 da Matriz/genética; Metaloproteinase 2 da Matriz/metabolismo; Proteínas dos Microfilamentos/genética; Proteínas dos Microfilamentos/metabolismo; Microscopia de Força Atômica; Proteínas Musculares/genética; Proteínas Musculares/metabolismo; Osteopontina/genética; Osteopontina/metabolismo; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Transdução de Sinais/genética; Transdução de Sinais/fisiologia; Calponinas

Palavras-chave

Extracellular matrix; Matrix stiffness; Smooth muscle cells; TGF-ß

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Miócitos de Músculo Liso Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biomaterials Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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