Mitochondrial Transcription Factor A Regulates Mycobacterium bovis-Induced IFN-ß Production by Modulating Mitochondrial DNA Replication in Macrophages.

Song, Yinjuan; Hussain, Tariq; Wang, Jie; Liao, Yi; Yue, Ruichao; Sabir, Naveed; Zhao, Deming; Zhou, Xiangmei

Song, Yinjuan; Hussain, Tariq; Wang, Jie; Liao, Yi; Yue, Ruichao; Sabir, Naveed; Zhao, Deming; Zhou, Xiangmei.

Afiliação

Song Y; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Hussain T; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Wang J; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Liao Y; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Yue R; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Sabir N; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhao D; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Zhou X; Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

J Infect Dis ; 221(3): 438-448, 2020 01 14.

Article em En | MEDLINE | ID: mdl-31495880

Assuntos

Replicação do DNA; DNA Mitocondrial/genética; Proteínas de Ligação a DNA/metabolismo; Proteínas de Grupo de Alta Mobilidade/metabolismo; Interferon beta/biossíntese; Macrófagos/imunologia; Mycobacterium bovis/imunologia; Tuberculose/imunologia; Tuberculose/veterinária; Animais; Linhagem Celular Tumoral; Citosol/metabolismo; DNA Mitocondrial/metabolismo; Proteínas de Ligação a DNA/genética; Técnicas de Silenciamento de Genes; Proteínas de Grupo de Alta Mobilidade/genética; Macrófagos/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Mitocôndrias/metabolismo; Mycobacterium bovis/metabolismo; Transdução de Sinais/genética; Tuberculose/microbiologia

Palavras-chave

Mycobacterium bovis; IFN-ß; TFAM; macrophage; mitochondrial DNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / DNA Mitocondrial / Proteínas de Grupo de Alta Mobilidade / Interferon beta / Proteínas de Ligação a DNA / Replicação do DNA / Macrófagos / Mycobacterium bovis Limite: Animals Idioma: En Revista: J Infect Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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