SnapShot: The RNA Exosome.

Puno, M Rhyan; Weick, Eva-Maria; Das, Mom; Lima, Christopher D

Puno, M Rhyan; Weick, Eva-Maria; Das, Mom; Lima, Christopher D.

Afiliação

Puno MR; Structural Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065.
Weick EM; Structural Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065.
Das M; Structural Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065.
Lima CD; Structural Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065; Howard Hughes Medical Institute, 1275 York Avenue, New York, NY 10065.

Cell ; 179(1): 282-282.e1, 2019 09 19.

Article em En | MEDLINE | ID: mdl-31539497

RESUMO

The RNA exosome is a 3' to 5' ribonuclease that plays a fundamental role in maturation, quality control, and turnover of nearly all types of RNA produced in eukaryotic cells. Here, we present an overview of the structure, composition, and functions of the RNA exosome, including various cytoplasmic and nuclear exosome co-factors and associated protein complexes. To view this SnapShot, open or download the PDF.

Assuntos

Complexo Multienzimático de Ribonucleases do Exossomo/metabolismo; Exossomos/metabolismo; RNA Mensageiro/metabolismo; RNA Ribossômico/metabolismo; Núcleo Celular/metabolismo; Citoplasma/metabolismo; Humanos; RNA Helicases/metabolismo; Estabilidade de RNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Mensageiro / RNA Ribossômico / Exossomos / Complexo Multienzimático de Ribonucleases do Exossomo Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article

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