Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-&#954;B Pathway in Preclinical Models of Pediatric High-Grade Glioma.

DeSisto, John A; Flannery, Patrick; Lemma, Rakeb; Pathak, Amrita; Mestnik, Shelby; Philips, Natalie; Bales, Natalie J; Kashyap, Trinayan; Moroze, Erin; Venkataraman, Sujatha; Kung, Andrew L; Carter, Bruce D; Landesman, Yosef; Vibhakar, Rajeev; Green, Adam L

Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma.

DeSisto, John A; Flannery, Patrick; Lemma, Rakeb; Pathak, Amrita; Mestnik, Shelby; Philips, Natalie; Bales, Natalie J; Kashyap, Trinayan; Moroze, Erin; Venkataraman, Sujatha; Kung, Andrew L; Carter, Bruce D; Landesman, Yosef; Vibhakar, Rajeev; Green, Adam L.

Afiliação

DeSisto JA; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Flannery P; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Lemma R; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Pathak A; Department of Biochemistry, Vanderbilt University Medical School, Nashville, Tennessee.
Mestnik S; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Philips N; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Bales NJ; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Kashyap T; Karyopharm Therapeutics, Inc., Newton, Massachusetts.
Moroze E; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Venkataraman S; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Kung AL; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Carter BD; Department of Biochemistry, Vanderbilt University Medical School, Nashville, Tennessee.
Landesman Y; Karyopharm Therapeutics, Inc., Newton, Massachusetts.
Vibhakar R; Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, Colorado.
Green AL; Children's Hospital Colorado, Aurora, Colorado.

Mol Cancer Ther ; 19(2): 540-551, 2020 02.

Article em En | MEDLINE | ID: mdl-31594826

Assuntos

Glioma/genética; Carioferinas/uso terapêutico; NF-kappa B/metabolismo; Receptores Citoplasmáticos e Nucleares/uso terapêutico; Receptores de Fator de Crescimento Neural/metabolismo; Humanos; Carioferinas/farmacologia; Gradação de Tumores; Receptores Citoplasmáticos e Nucleares/farmacologia; Transfecção; Proteína Exportina 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Receptores de Fator de Crescimento Neural / Receptores Citoplasmáticos e Nucleares / Carioferinas / Glioma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2020 Tipo de documento: Article

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