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A Loop-Mediated Isothermal Amplification Assay Targeting Neisseria gonorrhoeae penA-60.001.
Shimuta, Ken; Nakayama, Shu-Ichi; Takahashi, Hideyuki; Ohnishi, Makoto.
Afiliação
  • Shimuta K; Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan shimuta@niid.go.jp.
  • Nakayama SI; Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
  • Takahashi H; Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
  • Ohnishi M; Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Antimicrob Agents Chemother ; 64(1)2019 12 20.
Article em En | MEDLINE | ID: mdl-31658968
Ceftriaxone (CRO) is widely used as the first-line treatment for gonococcal infections. However, CRO-resistant Neisseria gonorrhoeae strains carrying mosaic penA-60.001 have emerged recently and disseminated worldwide. To meet the urgent need to detect these strains, we report here a loop-mediated isothermal amplification (LAMP) assay system that targets N. gonorrhoeaepenA-60.001. This assay system can differentiate N. gonorrhoeae strains carrying mosaic penA-60.001 from strains carrying other penA alleles.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ceftriaxona / Antibacterianos / Neisseria gonorrhoeae Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ceftriaxona / Antibacterianos / Neisseria gonorrhoeae Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão