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Relationship between alirocumab, PCSK9, and LDL-C levels in four phase 3 ODYSSEY trials using 75 and 150 mg doses.
Robinson, Jennifer G; Farnier, Michel; Kastelein, John J P; Roth, Eli M; Taskinen, Marja-Riitta; Colhoun, Helen M; Brunet, Aurelie; DiCioccio, A Thomas; Lecorps, Guillaume; Pordy, Robert; Baccara-Dinet, Marie T; Cannon, Christopher P.
Afiliação
  • Robinson JG; University of Iowa, Iowa City, IA, USA. Electronic address: jennifer-g-robinson@uiowa.edu.
  • Farnier M; Lipid Clinic, Point Médical and Department of Cardiology, CHU Dijon-Bourgogne, Dijon, France.
  • Kastelein JJP; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
  • Roth EM; The Sterling Research Group, Cincinnati, OH, USA.
  • Taskinen MR; Research Program Unit, Clinical and Molecular Metabolism, University of Helsinki, Finland.
  • Colhoun HM; University of Edinburgh, Edinburgh, UK.
  • Brunet A; Sanofi, Clinical Development, R&D, Montpellier, France.
  • DiCioccio AT; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
  • Lecorps G; Sanofi, Chilly-Mazarin, France.
  • Pordy R; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
  • Baccara-Dinet MT; Sanofi, Clinical Development, R&D, Montpellier, France.
  • Cannon CP; Harvard Clinical Research Institute, Boston, MA, USA.
J Clin Lipidol ; 13(6): 979-988.e10, 2019.
Article em En | MEDLINE | ID: mdl-31708410
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Humanizados / Pró-Proteína Convertase 9 / LDL-Colesterol Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Lipidol Assunto da revista: BIOQUIMICA / METABOLISMO Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Humanizados / Pró-Proteína Convertase 9 / LDL-Colesterol Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Lipidol Assunto da revista: BIOQUIMICA / METABOLISMO Ano de publicação: 2019 Tipo de documento: Article