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In silico model-based characterization of metabolic response to harsh sparging stress in fed-batch CHO cell cultures.
Hong, Jong Kwang; Yeo, Hock Chuan; Lakshmanan, Meiyappan; Han, Sung-Hyuk; Cha, Hyun Myoung; Han, Muri; Lee, Dong-Yup.
Afiliação
  • Hong JK; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, 138668, Singapore.
  • Yeo HC; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, 138668, Singapore.
  • Lakshmanan M; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, 138668, Singapore.
  • Han SH; Upstream process, GC Pharma R&D center, 107 Ihyun-ro, Giheung-gu, Yongin-si, Gyeonggi-do, 16926, Republic of Korea.
  • Cha HM; Upstream process, GC Pharma R&D center, 107 Ihyun-ro, Giheung-gu, Yongin-si, Gyeonggi-do, 16926, Republic of Korea.
  • Han M; Upstream process, GC Pharma R&D center, 107 Ihyun-ro, Giheung-gu, Yongin-si, Gyeonggi-do, 16926, Republic of Korea.
  • Lee DY; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, 138668, Singapore; School of Chemical Engineering, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea. Electronic address: dongyuplee@skku.e
J Biotechnol ; 308: 10-20, 2020 Jan 20.
Article em En | MEDLINE | ID: mdl-31756358
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Aminoácidos / Peróxido de Hidrogênio Limite: Animals Idioma: En Revista: J Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Singapura
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Aminoácidos / Peróxido de Hidrogênio Limite: Animals Idioma: En Revista: J Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Singapura