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Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses.
Iannielli, Angelo; Ugolini, Giovanni Stefano; Cordiglieri, Chiara; Bido, Simone; Rubio, Alicia; Colasante, Gaia; Valtorta, Marco; Cabassi, Tommaso; Rasponi, Marco; Broccoli, Vania.
Afiliação
  • Iannielli A; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy; CNR Institute of Neuroscience, 20129 Milan, Italy.
  • Ugolini GS; Department of Electronics, Information & Bioengineering, Politecnico di Milano, 20133 Milan, Italy.
  • Cordiglieri C; National Institute of Molecular Genetics "Romeo e Enrica Invernizzi" - INGM, 20122 Milan, Italy.
  • Bido S; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Rubio A; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy; CNR Institute of Neuroscience, 20129 Milan, Italy.
  • Colasante G; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Valtorta M; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy; CNR Institute of Neuroscience, 20129 Milan, Italy.
  • Cabassi T; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Rasponi M; Department of Electronics, Information & Bioengineering, Politecnico di Milano, 20133 Milan, Italy.
  • Broccoli V; Stem Cell and Neurogenesis Unit, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy; CNR Institute of Neuroscience, 20129 Milan, Italy. Electronic address: broccoli.vania@hsr.it.
Cell Rep ; 29(13): 4646-4656.e4, 2019 12 24.
Article em En | MEDLINE | ID: mdl-31875567
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Substância Negra / Neostriado / Dispositivos Lab-On-A-Chip / Neurônios Dopaminérgicos / GTP Fosfo-Hidrolases / Mitocôndrias Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Substância Negra / Neostriado / Dispositivos Lab-On-A-Chip / Neurônios Dopaminérgicos / GTP Fosfo-Hidrolases / Mitocôndrias Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália