3MA, 3-methyladenine; AAA, ATPases associated with various cellular activities; ACC1, acetyl-CoA carboxylase 1; ACC2, acetyl-CoA carboxylase 2; ACHE, acetylcholinesterase; ACOX1, acyl-CoA oxidase 1; ALD, autophagic-lysosomal degradation; AMPK1; AP-1, activator protein 1; ASK1, apoptosis signal-regulating kinase; ATF2, activating transcription factor 2; AdipoR1, gene of adiponectin receptor 1; Atg14, autophagy-related 14; CBZ, carbamazepine; CHIP E3 ubiquitin ligase; CHIP, carboxy-terminus of Hsc70-interacting protein; Cytochromes P450; Endoplasmic reticulum-associated degradation; FOXO, forkhead box O; Fas, fatty acid synthase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; INH, isoniazid; IRS1, insulin receptor substrate 1; Il-1ß, interleukin 1 ß; Il-6, interleukin 6; Insig1, insulin-induced gene 1; JNK1; Lpl, lipoprotein lipase; Mcp1, chemokine (C­C motif) ligand 1; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Pgc1, peroxisome proliferator-activated receptor coactivator 1; SREBP1c, sterol regulatory element binding transcription factor 1c; Scd1, stearoyl-coenzyme A desaturase; Tnf, tumor necrosis factor; UPD, ubiquitin (Ub)-dependent proteasomal degradation; Ub, ubiquitin; gp78/AMFR E3 ubiquitin ligase; gp78/AMFR, autocrine motility factor receptor; shRNAi, shRNA interference