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An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity.
Qassim, Ayub; Souzeau, Emmanuelle; Siggs, Owen M; Hassall, Mark M; Han, Xikun; Griffiths, Helen L; Frost, N Andrew; Vallabh, Neeru A; Kirwan, James F; Menon, Geeta; Cree, Angela J; Galanopoulos, Anna; Agar, Ashish; Healey, Paul R; Graham, Stuart L; Landers, John; Casson, Robert J; Gharahkhani, Puya; Willoughby, Colin E; Hewitt, Alex W; Lotery, Andrew J; MacGregor, Stuart; Craig, Jamie E.
Afiliação
  • Qassim A; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia. Electronic address: ayub.qassim@flinders.edu.au.
  • Souzeau E; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia.
  • Siggs OM; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia.
  • Hassall MM; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia.
  • Han X; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Griffiths HL; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Frost NA; Department of Ophthalmology, Torbay Hospital, Torquay, Devon, United Kingdom.
  • Vallabh NA; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom.
  • Kirwan JF; Department of Ophthalmology, Portsmouth Hospitals, Portsmouth, United Kingdom.
  • Menon G; Department of Ophthalmology, Frimley Park Hospital NHS Foundation Trust, Frimley, United Kingdom.
  • Cree AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Galanopoulos A; South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia.
  • Agar A; Department of Ophthalmology, Prince of Wales Hospital, Randwick, Australia.
  • Healey PR; Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.
  • Graham SL; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
  • Landers J; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia.
  • Casson RJ; South Australian Institute of Ophthalmology, University of Adelaide, Adelaide, Australia.
  • Gharahkhani P; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Willoughby CE; Biomedical Sciences Research Institute, Ulster University, Coleraine, United Kingdom; Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, United Kingdom.
  • Hewitt AW; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.
  • Lotery AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Craig JE; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, Australia.
Ophthalmology ; 127(7): 901-907, 2020 07.
Article em En | MEDLINE | ID: mdl-32081492

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acuidade Visual / Glaucoma de Ângulo Aberto / Estudo de Associação Genômica Ampla / Pressão Intraocular Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Ophthalmology Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acuidade Visual / Glaucoma de Ângulo Aberto / Estudo de Associação Genômica Ampla / Pressão Intraocular Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Ophthalmology Ano de publicação: 2020 Tipo de documento: Article