Visible-light-promoted acyl radical cascade reaction for accessing acylated isoquinoline-1,3(2H,4H)-dione derivatives.

Su, Yingpeng; Zhang, Rong; Xue, Wenxuan; Liu, Xuan; Zhao, Yanan; Wang, Ke-Hu; Huang, Danfeng; Huo, Congde; Hu, Yulai

Su, Yingpeng; Zhang, Rong; Xue, Wenxuan; Liu, Xuan; Zhao, Yanan; Wang, Ke-Hu; Huang, Danfeng; Huo, Congde; Hu, Yulai.

Afiliação

Su Y; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Zhang R; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Xue W; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Liu X; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Zhao Y; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Wang KH; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Huang D; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Huo C; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.
Hu Y; College of Chemistry and Chemical Engineering, Northwest Normal University, 967 Anning East Road, Lanzhou 730070, P. R. China. suyp51@nwnu.edu.cn huocongde1978@hotmail.com huyl@nwnu.edu.cn.

Org Biomol Chem ; 18(10): 1940-1948, 2020 03 14.

Article em En | MEDLINE | ID: mdl-32101246

ABSTRACT

ABSTRACT

A visible-light-promoted decarboxylative acyl radical acylation/cyclization cascade reaction of N-methacryloylbenzamides for accessing acylated isoquinoline-1,3(2H,4H)-dione derivatives was described. In this report, α-keto acids were used for generating acyl radicals and inducing radical acylations. This protocol features mild reaction conditions, operational practicality and a broad substrate scope.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article

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