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Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation.
Elledge, Susanna K; Tran, Hai L; Christian, Alec H; Steri, Veronica; Hann, Byron; Toste, F Dean; Chang, Christopher J; Wells, James A.
Afiliação
  • Elledge SK; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158.
  • Tran HL; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158.
  • Christian AH; Department of Chemistry, University of California, Berkeley, CA 94720.
  • Steri V; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158.
  • Hann B; Preclinical Therapeutics Core, University of California, San Francisco, CA 94158.
  • Toste FD; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158.
  • Chang CJ; Preclinical Therapeutics Core, University of California, San Francisco, CA 94158.
  • Wells JA; Department of Chemistry, University of California, Berkeley, CA 94720.
Proc Natl Acad Sci U S A ; 117(11): 5733-5740, 2020 03 17.
Article em En | MEDLINE | ID: mdl-32123103
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aziridinas / Imunoconjugados / Metionina Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aziridinas / Imunoconjugados / Metionina Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article