Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.

Dege, Carissa; Fegan, Katherine H; Creamer, J Philip; Berrien-Elliott, Melissa M; Luff, Stephanie A; Kim, Darren; Wagner, Julia A; Kingsley, Paul D; McGrath, Kathleen E; Fehniger, Todd A; Palis, James; Sturgeon, Christopher M

Dege, Carissa; Fegan, Katherine H; Creamer, J Philip; Berrien-Elliott, Melissa M; Luff, Stephanie A; Kim, Darren; Wagner, Julia A; Kingsley, Paul D; McGrath, Kathleen E; Fehniger, Todd A; Palis, James; Sturgeon, Christopher M.

Afiliação

Dege C; Department of Medicine, Division of Hematology, Washington University in St Louis, St. Louis, MO 63110, USA.
Fegan KH; Center for Pediatric Biomedical Research and Department of Pediatrics, University of Rochester, Rochester, NY 14642, USA.
Creamer JP; Department of Medicine, Division of Hematology, Washington University in St Louis, St. Louis, MO 63110, USA.
Berrien-Elliott MM; Department of Medicine, Division of Oncology, Washington University in St Louis, St. Louis, MO 63110, USA.
Luff SA; Department of Medicine, Division of Hematology, Washington University in St Louis, St. Louis, MO 63110, USA.
Kim D; Department of Medicine, Division of Hematology, Washington University in St Louis, St. Louis, MO 63110, USA.
Wagner JA; Department of Medicine, Division of Oncology, Washington University in St Louis, St. Louis, MO 63110, USA.
Kingsley PD; Center for Pediatric Biomedical Research and Department of Pediatrics, University of Rochester, Rochester, NY 14642, USA.
McGrath KE; Center for Pediatric Biomedical Research and Department of Pediatrics, University of Rochester, Rochester, NY 14642, USA.
Fehniger TA; Department of Medicine, Division of Oncology, Washington University in St Louis, St. Louis, MO 63110, USA.
Palis J; Center for Pediatric Biomedical Research and Department of Pediatrics, University of Rochester, Rochester, NY 14642, USA. Electronic address: james_palis@urmc.rochester.edu.
Sturgeon CM; Department of Medicine, Division of Hematology, Washington University in St Louis, St. Louis, MO 63110, USA; Department of Developmental Biology, Washington University in St Louis, St. Louis, MO 63110, USA; Center of Regenerative Medicine, Washington University in St Louis, St. Louis, MO 63110, USA.

Dev Cell ; 53(2): 229-239.e7, 2020 04 20.

Article em En | MEDLINE | ID: mdl-32197069

Assuntos

Diferenciação Celular; Linhagem da Célula; Células-Tronco Embrionárias/citologia; Células Precursoras Eritroides/citologia; Células-Tronco Hematopoéticas/citologia; Células Matadoras Naturais/patologia; Células Progenitoras Mieloides/citologia; Animais; Células-Tronco Embrionárias/metabolismo; Células Precursoras Eritroides/metabolismo; Feminino; Hematopoese; Células-Tronco Hematopoéticas/metabolismo; Humanos; Células Matadoras Naturais/metabolismo; Masculino; Camundongos; Células Progenitoras Mieloides/metabolismo; Saco Vitelino

Palavras-chave

EMP; HSC-independent; adoptive immunotherapy; definitive hematopoiesis; erythro-myeloid progenitor; human pluripotent stem cells; natural killer cells; ontogeny; primitive hematopoiesis; yolk sac

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Células Matadoras Naturais / Células Precursoras Eritroides / Diferenciação Celular / Linhagem da Célula / Células Progenitoras Mieloides / Células-Tronco Embrionárias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Dev Cell Assunto da revista: EMBRIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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