SnapShot: Natural Killer Cells.

Crinier, Adeline; Narni-Mancinelli, Emilie; Ugolini, Sophie; Vivier, Eric

Crinier, Adeline; Narni-Mancinelli, Emilie; Ugolini, Sophie; Vivier, Eric.

Afiliação

Crinier A; Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Narni-Mancinelli E; Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Ugolini S; Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Vivier E; Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France; Immunology, Marseille Immunopole, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille, France; Innate Pharma Research Laboratories, Innate Pharma, Marseille, France.

Cell ; 180(6): 1280-1280.e1, 2020 03 19.

Article em En | MEDLINE | ID: mdl-32200803

ABSTRACT

ABSTRACT

NK cells are broadly distributed innate lymphoid cells (ILCs) encompassing distinct populations based on CD11b and CD27 expression in mice or CD56 intensity in humans. Involved in anti-viral and anti-tumor immunity thanks to their cytokines and chemokines secretion as well as their cytotoxic capabilities, NK cells have emerged as a promising therapeutic target in several solid tumors and hematological malignancies. To view this Snapshot, open or download the PDF.

Assuntos

Células Matadoras Naturais/imunologia; Células Matadoras Naturais/metabolismo; Células Matadoras Naturais/fisiologia; Animais; Citocinas/metabolismo; Humanos; Imunidade Inata; Imunoterapia Ativa/métodos; Camundongos; Neoplasias/imunologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França

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