Accurately Predicting Mutation-Caused Stability Changes from Protein Sequences Using Extreme Gradient Boosting.

Lv, Xuan; Chen, Jianwen; Lu, Yutong; Chen, Zhiguang; Xiao, Nong; Yang, Yuedong

Lv, Xuan; Chen, Jianwen; Lu, Yutong; Chen, Zhiguang; Xiao, Nong; Yang, Yuedong.

Afiliação

Lv X; State Key Laboratory of High-Performance Computing, School of Computer Science, National University of Defense Technology, Changsha, Hunan 410073, China.
Chen J; School of Data and Computer Science, Sun Yat-sen University, Guangzhou, Guangdong 510275, China.
Lu Y; School of Data and Computer Science, Sun Yat-sen University, Guangzhou, Guangdong 510275, China.
Chen Z; School of Data and Computer Science, Sun Yat-sen University, Guangzhou, Guangdong 510275, China.
Xiao N; State Key Laboratory of High-Performance Computing, School of Computer Science, National University of Defense Technology, Changsha, Hunan 410073, China.
Yang Y; School of Data and Computer Science, Sun Yat-sen University, Guangzhou, Guangdong 510275, China.

J Chem Inf Model ; 60(4): 2388-2395, 2020 04 27.

Article em En | MEDLINE | ID: mdl-32203653

Assuntos

Mutação; Mutação Puntual; Proteínas; Sequência de Aminoácidos; Estabilidade Proteica; Proteínas/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Mutação Puntual / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Chem Inf Model Assunto da revista: INFORMATICA MEDICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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