CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression.

Fousek, Kristen; Watanabe, Junji; Joseph, Sujith K; George, Ann; An, Xingyue; Byrd, Tiara T; Morris, Jessica S; Luong, Annie; Martínez-Paniagua, Melisa A; Sanber, Khaled; Navai, Shoba A; Gad, Ahmed Z; Salsman, Vita S; Mathew, Pretty R; Kim, Hye Na; Wagner, Dimitrios L; Brunetti, Lorenzo; Jang, Albert; Baker, Matthew L; Varadarajan, Navin; Hegde, Meenakshi; Kim, Yong-Mi; Heisterkamp, Nora; Abdel-Azim, Hisham; Ahmed, Nabil

Fousek, Kristen; Watanabe, Junji; Joseph, Sujith K; George, Ann; An, Xingyue; Byrd, Tiara T; Morris, Jessica S; Luong, Annie; Martínez-Paniagua, Melisa A; Sanber, Khaled; Navai, Shoba A; Gad, Ahmed Z; Salsman, Vita S; Mathew, Pretty R; Kim, Hye Na; Wagner, Dimitrios L; Brunetti, Lorenzo; Jang, Albert; Baker, Matthew L; Varadarajan, Navin; Hegde, Meenakshi; Kim, Yong-Mi; Heisterkamp, Nora; Abdel-Azim, Hisham; Ahmed, Nabil.

Afiliação

Fousek K; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.
Watanabe J; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Joseph SK; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
George A; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
An X; Division of Hematology, Oncology and Bone Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Byrd TT; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Morris JS; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Luong A; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Martínez-Paniagua MA; Division of Hematology, Oncology and Bone Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Sanber K; Department of Chemical and Biomolecular Engineering, University of Houston, Houston, TX, USA.
Navai SA; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.
Gad AZ; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Salsman VS; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Mathew PR; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Kim HN; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.
Wagner DL; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Brunetti L; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Jang A; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Baker ML; Division of Hematology, Oncology and Bone Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Varadarajan N; University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Hegde M; Department of Chemical and Biomolecular Engineering, University of Houston, Houston, TX, USA.
Kim YM; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.
Heisterkamp N; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Abdel-Azim H; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Ahmed N; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX, USA.

Leukemia ; 35(1): 75-89, 2021 01.

Article em En | MEDLINE | ID: mdl-32205861

Assuntos

Antígenos CD19/imunologia; Imunoterapia Adotiva; Leucemia de Células B/imunologia; Leucemia de Células B/metabolismo; Receptores de Antígenos de Linfócitos T/imunologia; Receptores de Antígenos Quiméricos/imunologia; Linfócitos T/imunologia; Linfócitos T/metabolismo; Animais; Antígenos CD19/química; Antígenos de Neoplasias; Biomarcadores; Linhagem Celular Tumoral; Citocinas/metabolismo; Citotoxicidade Imunológica; Modelos Animais de Doenças; Expressão Gênica; Humanos; Imunoterapia Adotiva/métodos; Leucemia de Células B/genética; Leucemia de Células B/terapia; Camundongos Transgênicos; Ligação Proteica; Receptores de Antígenos de Linfócitos T/metabolismo; Receptores de Antígenos Quiméricos/genética; Receptores de Antígenos Quiméricos/metabolismo; Relação Estrutura-Atividade; Transdução Genética; Transgenes; Resultado do Tratamento; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Linfócitos T / Leucemia de Células B / Imunoterapia Adotiva / Antígenos CD19 / Receptores de Antígenos Quiméricos Limite: Animals / Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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