(quantitative) Structure­activity relationships; AI, Artificial Intelligence; AOPs, Adverse Outcome Pathways; API, Application Programming interface; CG, coarse-grained (model); CNTs, carbon nanotubes; Computational toxicology; Engineered nanomaterials; FAIR, Findable Accessible Inter-operable and Re-usable; GUI, Graphical Processing Unit; HOMO-LUMO, Highest Occupied Molecular Orbital Lowest Unoccupied Molecular Orbital; Hazard assessment; IATA, Integrated Approaches to Testing and Assessment; Integrated approach for testing and assessment; KE, key events; MIE, molecular initiating events; ML, machine learning; MOA, mechanism (mode) of action; MWCNT, multi-walled carbon nanotubes; Machine learning; NMs, nanomaterials; Nanoinformatics; OECD, Organisation for Economic Co-operation and Development; PBPK, Physiologically Based PharmacoKinetics; PC, Protein Corona; PChem, Physicochemical; PTGS, Predictive Toxicogenomics Space; Predictive modelling; QC, quantum-chemical; QM, quantum-mechanical; QSAR, quantitative structure-activity relationship; QSPR, quantitative structure-property relationship; RA, risk assessment; REST, Representational State Transfer; ROS, reactive oxygen species; Read across; SAR, structure-activity relationship; SMILES, Simplified Molecular Input Line Entry System; SOPs, standard operating procedures; Safe-by-design; Toxicogenomics