Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice.

Nozawa, Kaori; Zhang, Qian; Miyata, Haruhiko; Devlin, Darius J; Yu, Zhifeng; Oura, Seiya; Koyano, Takayuki; Matsuyama, Makoto; Ikawa, Masahito; Matzuk, Martin M

Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice.

Nozawa, Kaori; Zhang, Qian; Miyata, Haruhiko; Devlin, Darius J; Yu, Zhifeng; Oura, Seiya; Koyano, Takayuki; Matsuyama, Makoto; Ikawa, Masahito; Matzuk, Martin M.

Afiliação

Nozawa K; Center for Drug Discovery, Baylor College of Medicine, Houston, TX.
Zhang Q; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX.
Miyata H; Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Devlin DJ; Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Yu Z; Center for Drug Discovery, Baylor College of Medicine, Houston, TX.
Oura S; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX.
Koyano T; Interdepartmental Program in Translational Biology & Molecular Medicine, Baylor College of Medicine, Houston, TX.
Matsuyama M; Center for Drug Discovery, Baylor College of Medicine, Houston, TX.
Ikawa M; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX.
Matzuk MM; Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.

Biol Reprod ; 103(2): 244-253, 2020 08 04.

Article em En | MEDLINE | ID: mdl-32301969

Assuntos

Infertilidade Masculina/genética; Proteínas de Plasma Seminal/genética; Motilidade dos Espermatozoides/genética; Espermatogênese/genética; Teratozoospermia/genética; Animais; Feminino; Masculino; Camundongos; Camundongos Knockout; Espermatozoides/metabolismo

Palavras-chave

fertilization; male infertility; null mutation/knockout; sperm; spermatogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Motilidade dos Espermatozoides / Espermatogênese / Proteínas de Plasma Seminal / Teratozoospermia / Infertilidade Masculina Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Biol Reprod Ano de publicação: 2020 Tipo de documento: Article

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