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Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical-stage soluble guanylate cyclase stimulator in rats.
Banijamali, Ali R; Carvalho, Andrew E; Wakefield, James D; Germano, Peter; Barden, Timothy C; Tobin, Jenny V; Zimmer, Daniel P; Masferrer, Jaime L; Profy, Albert T; Currie, Mark G; Todd Milne, G.
Afiliação
  • Banijamali AR; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Carvalho AE; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Wakefield JD; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Germano P; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Barden TC; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Tobin JV; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Zimmer DP; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Masferrer JL; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Profy AT; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Currie MG; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
  • Todd Milne G; Department of Drug Metabolism and Pharmacokinetics, Cyclerion Therapeutics, Cambridge, MA, USA.
Pharmacol Res Perspect ; 8(2): e00579, 2020 04.
Article em En | MEDLINE | ID: mdl-32314550
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas Limite: Animals Idioma: En Revista: Pharmacol Res Perspect Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas Limite: Animals Idioma: En Revista: Pharmacol Res Perspect Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos