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A new medical imaging technique for diagnosing dermatologic diseases: A clue to treatment choices.
Fioranelli, Massimo; Sepehri, Alireza; Roccia, Maria Grazia; Carolina, Aracena Jahaira; Binic, Iva; Golubovic, Masa; Tirant, Michael; Van Thuong, Nguyen; Sigova, Julia; Lotti, Torello; Beesham, Aroonkumar.
Afiliação
  • Fioranelli M; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Sepehri A; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Roccia MG; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Carolina AJ; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Binic I; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Golubovic M; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Tirant M; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Van Thuong N; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Sigova J; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Lotti T; Department of Nuclear, Sub-Nuclear and Radiation Physics, Guglielmo Marconi University, Rome, Italy.
  • Beesham A; Faculty of Natural Sciences, Mangosuthu University of Technology, Jacobs, South Africa.
Dermatol Ther ; 33(3): e13405, 2020 05.
Article em En | MEDLINE | ID: mdl-32314855
Recently, it has been shown that DNA could emit some waves which carry main information about its evolution. Using this idea, we design a new method to image the behavior of skin cells, especially melanocytes, and diagnose their damage. In this method, we make use of a circuit which is formed from DNAs within the damaged melanocytes, a graphene sheet, DNAs within the healthy cells, and a scope. To amplify exchanged waves between hexagonal and pentagonal manifolds of DNAs, we induce some defects in the graphene sheets and replace some hexagonal molecules by pentagonal ones to build a structure similar to the structure of DNAs. We show that unprotected exposure to UVA and UVB damages the DNA in melanocyte cells, producing genetic defects, or mutations, that can lead to exchanged waves between cells and the emergence of a current in our circuit. By analyzing the evolution of this current, we can estimate the rate of destruction in melanocytes, and predict the emergence of cancer.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Melanócitos Tipo de estudo: Diagnostic_studies Idioma: En Revista: Dermatol Ther Assunto da revista: DERMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Melanócitos Tipo de estudo: Diagnostic_studies Idioma: En Revista: Dermatol Ther Assunto da revista: DERMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália