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Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms.
Ghani, Rohma; Mullish, Benjamin H; McDonald, Julie A K; Ghazy, Anan; Williams, Horace R T; Brannigan, Eimear T; Mookerjee, Siddharth; Satta, Giovanni; Gilchrist, Mark; Duncan, Neill; Corbett, Richard; Innes, Andrew J; Pavlu, Jirí; Thursz, Mark R; Davies, Frances; Marchesi, Julian R.
Afiliação
  • Ghani R; Division of Digestive Diseases, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, United Kingdom.
  • Mullish BH; Department of Infection, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • McDonald JAK; Division of Digestive Diseases, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, United Kingdom.
  • Ghazy A; Department of Gastroenterology and Hepatology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Williams HRT; Division of Digestive Diseases, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, United Kingdom.
  • Brannigan ET; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
  • Mookerjee S; Department of Infection, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Satta G; Division of Digestive Diseases, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, United Kingdom.
  • Gilchrist M; Department of Gastroenterology and Hepatology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Duncan N; Department of Infection, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Corbett R; Department of Infection, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Innes AJ; Department of Infection, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Pavlu J; Department of Infection, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Thursz MR; Department of Renal Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Davies F; Department of Renal Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Marchesi JR; Centre for Haematology, Imperial College London, and Hammersmith Hospital, Imperial College London NHS Trust, London, United Kingdom.
Clin Infect Dis ; 72(8): 1444-1447, 2021 04 26.
Article em En | MEDLINE | ID: mdl-32681643
ABSTRACT
Fecal microbiota transplantation (FMT) yields variable intestinal decolonization results for multidrug-resistant organisms (MDROs). This study showed significant reductions in antibiotic duration, bacteremia, and length of stay in 20 patients colonized/infected with MDRO receiving FMT (compared with pre-FMT history, and a matched group not receiving FMT), despite modest decolonization rates.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Microbiota Fecal / Microbioma Gastrointestinal Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Microbiota Fecal / Microbioma Gastrointestinal Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido