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Ilimaquinone inhibits neovascular age-related macular degeneration through modulation of Wnt/ß-catenin and p53 pathways.
Son, Younglim; Lim, Daehan; Park, Seoyoung; Song, Im-Sook; Kim, Joo-Hyun; Shin, Sora; Jang, Hoik; Liu, Kwang-Hyeon; O, Yuseok; Song, Gyu-Yong; Kang, Wonku; Cho, Yun-Seok; Na, MinKyun; Chung, Hyewon; Oh, Sangtaek.
Afiliação
  • Son Y; Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, 02707, Republic of Korea.
  • Lim D; Department of Ophthalmology, Konkuk University School of Medicine, Seoul, 05030, Republic of Korea.
  • Park S; Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, 02707, Republic of Korea.
  • Song IS; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
  • Kim JH; Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, 02707, Republic of Korea.
  • Shin S; Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, 02707, Republic of Korea.
  • Jang H; Department of Ophthalmology, Konkuk University School of Medicine, Seoul, 05030, Republic of Korea.
  • Liu KH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
  • O Y; College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea.
  • Song GY; College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea.
  • Kang W; College of Pharmacy, Chung-Ang Univsersity, Seoul, 06974, Republic of Korea.
  • Cho YS; R&D center, Hanlim Pharm. Co., Ltd., Seoul, 06634, Republic of Korea.
  • Na M; College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea. Electronic address: mkna@cnu.ac.kr.
  • Chung H; Department of Ophthalmology, Konkuk University School of Medicine, Seoul, 05030, Republic of Korea. Electronic address: hchung@kuh.ac.kr.
  • Oh S; Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, 02707, Republic of Korea. Electronic address: ohsa@kookmin.ac.kr.
Pharmacol Res ; 161: 105146, 2020 11.
Article em En | MEDLINE | ID: mdl-32814173
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinonas / Vasos Retinianos / Sesquiterpenos / Neovascularização Retiniana / Proteína Supressora de Tumor p53 / Neovascularização de Coroide / Inibidores da Angiogênese / Beta Catenina / Via de Sinalização Wnt / Degeneração Macular Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinonas / Vasos Retinianos / Sesquiterpenos / Neovascularização Retiniana / Proteína Supressora de Tumor p53 / Neovascularização de Coroide / Inibidores da Angiogênese / Beta Catenina / Via de Sinalização Wnt / Degeneração Macular Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article