Cooperative Heteroligand Interaction with G-Quadruplexes Shows Evidence of Allosteric Binding.

Pandey, Shankar; Li, Yuanyuan; Young, Montwaun D; Mandal, Shankar; Lu, Laichun; Shelley, Jacob T; Mao, Hanbin

Pandey, Shankar; Li, Yuanyuan; Young, Montwaun D; Mandal, Shankar; Lu, Laichun; Shelley, Jacob T; Mao, Hanbin.

Afiliação

Pandey S; Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44242, United States.
Li Y; Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44242, United States.
Young MD; Department of Pharmacy, Daping Hospital, Army Medical University, Chongqing 400042, China.
Mandal S; Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York 12180, United States.
Lu L; Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44242, United States.
Shelley JT; National Institute for Drug Clinical Trial, Beijing Tongren Hospital, Capital Medical University, 1 Dongjiaominxiang Road, Beijing 100730, China.
Mao H; Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York 12180, United States.

Biochemistry ; 59(37): 3438-3446, 2020 09 22.

Article em En | MEDLINE | ID: mdl-32833433

Assuntos

Aminoquinolinas/metabolismo; Quadruplex G; Oxazóis/metabolismo; Ácidos Picolínicos/metabolismo; Telômero/química; Telômero/metabolismo; Sítio Alostérico; Sítios de Ligação; Humanos; Ligantes; Modelos Moleculares

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazóis / Ácidos Picolínicos / Telômero / Quadruplex G / Aminoquinolinas Limite: Humans Idioma: En Revista: Biochemistry Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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