Estimation of the area under concentration-time curve of polymyxin B based on limited sampling concentrations in Chinese patients with severe pneumonia.

Chen, Wenqian; Liu, Huifang; Wang, Qianlin; Wang, Xiaoxing; Kong, Xudong; Wang, Xiaoxue; Zhang, Xianglin; Zhan, Qingyuan; Li, Pengmei

Chen, Wenqian; Liu, Huifang; Wang, Qianlin; Wang, Xiaoxing; Kong, Xudong; Wang, Xiaoxue; Zhang, Xianglin; Zhan, Qingyuan; Li, Pengmei.

Afiliação

Chen W; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China.
Liu H; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China.
Wang Q; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
Wang X; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China.
Kong X; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China.
Wang X; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China.
Zhang X; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China.
Zhan Q; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, 100029, China.
Li P; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China. lipengmei@yeah.net.

Eur J Clin Pharmacol ; 77(1): 95-105, 2021 Jan.

Article em En | MEDLINE | ID: mdl-32875388

Assuntos

Antibacterianos/sangue; Área Sob a Curva; Modelos Biológicos; Pneumonia/sangue; Polimixina B/sangue; Adulto; Idoso; Idoso de 80 Anos ou mais; Antibacterianos/farmacocinética; Povo Asiático; Monitoramento de Medicamentos; Feminino; Humanos; Masculino; Testes de Sensibilidade Microbiana; Pessoa de Meia-Idade; Pneumonia/tratamento farmacológico; Pneumonia/metabolismo; Polimixina B/farmacocinética

Palavras-chave

AUC; Limited sampling strategy; Pharmacokinetics; Polymyxin B; Therapeutic drug monitoring

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Polimixina B / Área Sob a Curva / Antibacterianos / Modelos Biológicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Clin Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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