Delayed treatment-free response after romiplostim discontinuation in pediatric chronic immune thrombocytopenia.
Yeungnam Univ J Med
; 38(2): 165-168, 2021 Apr.
Article
em En
| MEDLINE
| ID: mdl-32891076
ABSTRACT
We report the case of a 16-month-old patient with chronic immune thrombocytopenia (ITP) patient who experienced delayed treatment-free response (TFR) after romiplostim treatment. He received intravenous immunoglobulin every month to maintain a platelet count above 20,000/µL for 2 years. Thereafter, he received rituximab and cyclosporine as second-line therapy, with no response, followed by romiplostim. After 4 weeks of treatment, the platelet count was maintained above 50,000/µL. Following 7 months of treatment, he discontinued romiplostim, and the platelet count decreased. His platelet counts remained above 50,000/µL, without any bleeding symptoms, 2 years after romiplostim discontinuation. This is the first report of TFR after romiplostim treatment in pediatric chronic ITP.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Yeungnam Univ J Med
Ano de publicação:
2021
Tipo de documento:
Article