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A "Switch" in Time through Genes Aligned: Unraveling the Genomic Landscape of HSC Development.
Apostol, April C; López, Diego A; Beaudin, Anna E.
Afiliação
  • Apostol AC; Quantitative and Systems Biology Graduate Program, University of California-Merced, Merced, CA, USA.
  • López DA; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: diego.lopez@path.utah.edu.
  • Beaudin AE; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: anna.beaudin@hsc.utah.edu.
Cell Stem Cell ; 27(5): 695-697, 2020 11 05.
Article em En | MEDLINE | ID: mdl-33157043
Seeking to define the "switch" from fetal to adult hematopoiesis, Li et al. (2020) performed extensive genomic and epigenomic profiling of hematopoietic stem and progenitor cells across ontogeny (as explored in this issue of Cell Stem Cell). Gradual and stochastic changes in genomic and epigenomic regulation suggest the absence of any specific regulator.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Análise de Célula Única Idioma: En Revista: Cell Stem Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Análise de Célula Única Idioma: En Revista: Cell Stem Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos