Insulinoma induces a hyperinsulinemia-mediated decrease of GLUT2 and GLP1 receptor in normal pancreatic ß-cells.

Sho, H; Fukui, K; Yoneda, S; Toyoda, S; Ozawa, H; Ishibashi, C; Fujita, Y; Eguchi, H; Kozawa, J; Shimomura, I

Sho, H; Fukui, K; Yoneda, S; Toyoda, S; Ozawa, H; Ishibashi, C; Fujita, Y; Eguchi, H; Kozawa, J; Shimomura, I.

Afiliação

Sho H; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Fukui K; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan. Electronic address: kfukui@endmet.med.osaka-u.ac.jp.
Yoneda S; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Toyoda S; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Ozawa H; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Ishibashi C; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Fujita Y; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan; Departments of Community Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Eguchi H; Departments of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Kozawa J; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan; Departments of Diabetes Care Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Shimomura I; Departments of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.

Biochem Biophys Res Commun ; 534: 702-706, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33199025

Assuntos

Receptor do Peptídeo Semelhante ao Glucagon 1/metabolismo; Transportador de Glucose Tipo 2/metabolismo; Hiperinsulinismo/etiologia; Insulinoma/cirurgia; Neoplasias Pancreáticas/cirurgia; Idoso; Animais; Linhagem Celular; Feminino; Receptor do Peptídeo Semelhante ao Glucagon 1/genética; Transportador de Glucose Tipo 2/genética; Humanos; Insulina/farmacologia; Secreção de Insulina; Células Secretoras de Insulina/efeitos dos fármacos; Células Secretoras de Insulina/metabolismo; Insulinoma/metabolismo; Masculino; Camundongos; Pessoa de Meia-Idade; Neoplasias Pancreáticas/metabolismo; Período Pós-Operatório

Palavras-chave

Glucagon-like peptide 1 receptor; Glucose transporter 2; Insulinoma; Pancreatic ß-cell; Postoperative hyperglycemia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Transportador de Glucose Tipo 2 / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hiperinsulinismo / Insulinoma Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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