Pharmacokinetics under the COVID-19 storm.

Pilla Reddy, Venkatesh; El-Khateeb, Eman; Jo, Heeseung; Giovino, Natalie; Lythgoe, Emily; Sharma, Shringi; Tang, Weifeng; Jamei, Masoud; Rastomi-Hodjegan, Amin

Pilla Reddy, Venkatesh; El-Khateeb, Eman; Jo, Heeseung; Giovino, Natalie; Lythgoe, Emily; Sharma, Shringi; Tang, Weifeng; Jamei, Masoud; Rastomi-Hodjegan, Amin.

Afiliação

Pilla Reddy V; Modelling & Simulation, Early Oncology, R&D Oncology, AstraZeneca, Cambridge, UK.
El-Khateeb E; Clinical Pharmacology and Quantitative Pharmacology, R&D, AstraZeneca, Cambridge, UK.
Jo H; Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, UK.
Giovino N; Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Lythgoe E; Modelling & Simulation, Early Oncology, R&D Oncology, AstraZeneca, Cambridge, UK.
Sharma S; Early Oncology Clinical, R&D Oncology, AstraZeneca, Boston, USA.
Tang W; R&D Biopharmaceuticals, AstraZeneca, Cambridge, UK.
Jamei M; Clinical Pharmacology and Quantitative Pharmacology, R&D, AstraZeneca, USA.
Rastomi-Hodjegan A; Clinical Pharmacology and Quantitative Pharmacology, R&D, AstraZeneca, USA.

Br J Clin Pharmacol ; 89(1): 158-186, 2023 01.

Article em En | MEDLINE | ID: mdl-33226664

Assuntos

COVID-19; Hepatopatias; Humanos; Idoso; SARS-CoV-2; Interações Medicamentosas; Hidroxicloroquina; Modelos Biológicos; Farmacocinética; Simulação por Computador

Palavras-chave

ADME; COVID-19; Drug-Drug Interactions; M&S; PBPK; PKPD; cytokine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 / Hepatopatias Tipo de estudo: Prognostic_studies Limite: Aged / Humans Idioma: En Revista: Br J Clin Pharmacol Ano de publicação: 2023 Tipo de documento: Article

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