Dysregulation of Endobiotic Homeostasis Mechanisms: Novel Insights into Adverse Pharmacokinetic Interactions between Illicit Substances and Clinical Drugs.
ACS Chem Neurosci
; 11(24): 4021-4023, 2020 12 16.
Article
em En
| MEDLINE
| ID: mdl-33232117
ABSTRACT
Many patients with a variety of medical conditions take illicit substances concomitantly with clinical drugs. This concomitant usage can lead to life-threatening adverse events. Despite the evidence that these adverse events can be caused by pharmacokinetic interactions, the underlying mechanisms are poorly understood. Investigation of mechanisms involved in dysregulation of endobiotic homeostasis during the concomitant usage of illicit substances with clinical drugs could provide novel insights into pharmacokinetic mechanisms of adverse interactions between illicit substances and clinical drugs.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Drogas Ilícitas
/
Transtornos Relacionados ao Uso de Substâncias
Limite:
Humans
Idioma:
En
Revista:
ACS Chem Neurosci
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Estados Unidos