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Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease.
Sidhom, Eriene-Heidi; Kim, Choah; Kost-Alimova, Maria; Ting, May Theng; Keller, Keith; Avila-Pacheco, Julian; Watts, Andrew Jb; Vernon, Katherine A; Marshall, Jamie L; Reyes-Bricio, Estefanía; Racette, Matthew; Wieder, Nicolas; Kleiner, Giulio; Grinkevich, Elizabeth J; Chen, Fei; Weins, Astrid; Clish, Clary B; Shaw, Jillian L; Quinzii, Catarina M; Greka, Anna.
Afiliação
  • Sidhom EH; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Kim C; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Kost-Alimova M; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Ting MT; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Keller K; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Avila-Pacheco J; Department of Neurology, Columbia University Medical Center, New York, New York, USA.
  • Watts AJ; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Vernon KA; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Marshall JL; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Reyes-Bricio E; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Racette M; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Wieder N; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Kleiner G; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Grinkevich EJ; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Chen F; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Weins A; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Clish CB; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Shaw JL; Department of Neurology, Columbia University Medical Center, New York, New York, USA.
  • Quinzii CM; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Greka A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
J Clin Invest ; 131(5)2021 03 01.
Article em En | MEDLINE | ID: mdl-33444290
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Ataxia / Peroxidação de Lipídeos / Ubiquinona / Debilidade Muscular / Sistema de Sinalização das MAP Quinases / Doenças Mitocondriais / Proteínas Proto-Oncogênicas B-raf / Podócitos / Indenos Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Ataxia / Peroxidação de Lipídeos / Ubiquinona / Debilidade Muscular / Sistema de Sinalização das MAP Quinases / Doenças Mitocondriais / Proteínas Proto-Oncogênicas B-raf / Podócitos / Indenos Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos