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Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.
Xiao, Deqing; John Ling, Kah Hiing; Tarnowski, Thomas; Humeniuk, Rita; German, Polina; Mathias, Anita; Chu, Jasper; Chen, Yuan-Shek; van Ingen, Eric.
Afiliação
  • Xiao D; Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA. Electronic address: deqing.xiao@gilead.com.
  • John Ling KH; Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA.
  • Tarnowski T; Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA.
  • Humeniuk R; Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA.
  • German P; Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA.
  • Mathias A; Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA.
  • Chu J; QPS, LLC, Delaware Technology Park, 3 Innovation Way, Suite 240, Newark, DE, USA.
  • Chen YS; QPS, LLC, Delaware Technology Park, 3 Innovation Way, Suite 240, Newark, DE, USA.
  • van Ingen E; QPS, LLC, Delaware Technology Park, 3 Innovation Way, Suite 240, Newark, DE, USA.
Anal Biochem ; 617: 114118, 2021 03 15.
Article em En | MEDLINE | ID: mdl-33508271
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pirróis / Triazinas / Monofosfato de Adenosina / Monitoramento de Medicamentos / Alanina / Espectrometria de Massas em Tandem / Furanos Limite: Humans Idioma: En Revista: Anal Biochem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pirróis / Triazinas / Monofosfato de Adenosina / Monitoramento de Medicamentos / Alanina / Espectrometria de Massas em Tandem / Furanos Limite: Humans Idioma: En Revista: Anal Biochem Ano de publicação: 2021 Tipo de documento: Article