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IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
Mucciolo, Gianluca; Curcio, Claudia; Roux, Cecilia; Li, Wanda Y; Capello, Michela; Curto, Roberta; Chiarle, Roberto; Giordano, Daniele; Satolli, Maria Antonietta; Lawlor, Rita; Scarpa, Aldo; Lukac, Pavol; Stakheev, Dmitry; Provero, Paolo; Vannucci, Luca; Mak, Tak W; Novelli, Francesco; Cappello, Paola.
Afiliação
  • Mucciolo G; Laboratory of Tumor Immunology, Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, University of Torino, 10126 Torino, Italy.
  • Curcio C; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Roux C; Laboratory of Tumor Immunology, Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, University of Torino, 10126 Torino, Italy.
  • Li WY; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Capello M; Laboratory of Tumor Immunology, Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, University of Torino, 10126 Torino, Italy.
  • Curto R; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Chiarle R; Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
  • Giordano D; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Satolli MA; Laboratory of Tumor Immunology, Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, University of Torino, 10126 Torino, Italy.
  • Lawlor R; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Scarpa A; Laboratory of Tumor Immunology, Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, University of Torino, 10126 Torino, Italy.
  • Lukac P; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Stakheev D; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115.
  • Provero P; Laboratory of Tumor Immunology, Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, University of Torino, 10126 Torino, Italy.
  • Vannucci L; Medical Oncology Division, Centro Oncologico Ematologico Subalpino, Città della Salute e della Scienza di Torino, Department of Oncology, University of Torino, 10126 Torino, Italy.
  • Mak TW; Applied Research Center (ARC-NET), University of Verona, 37134 Verona, Italy.
  • Novelli F; Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
  • Cappello P; Applied Research Center (ARC-NET), University of Verona, 37134 Verona, Italy.
Proc Natl Acad Sci U S A ; 118(6)2021 02 09.
Article em En | MEDLINE | ID: mdl-33526692
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Receptores de Interleucina / Interleucina-17 / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Receptores de Interleucina / Interleucina-17 / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália