Benralizumab restores gene and microRNA expression involved in steroid sensitivity in severe asthma.

Hirai, Keita; Uehara, Sekiko; Shirai, Toshihiro; Rachi, Yuuka; Kimura, Tomoki; Akamatsu, Taisuke; Itoh, Kunihiko

Hirai, Keita; Uehara, Sekiko; Shirai, Toshihiro; Rachi, Yuuka; Kimura, Tomoki; Akamatsu, Taisuke; Itoh, Kunihiko.

Afiliação

Hirai K; Department of Clinical Pharmacology & Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Uehara S; Laboratory of Clinical Pharmacogenomics, Shizuoka General Hospital, Shizuoka, Japan.
Shirai T; Department of Clinical Pharmacology & Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Rachi Y; Department of Respiratory Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Kimura T; Department of Clinical Pharmacology & Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Akamatsu T; Department of Clinical Pharmacology & Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Itoh K; Department of Respiratory Medicine, Shizuoka General Hospital, Shizuoka, Japan.

Allergy ; 76(8): 2589-2592, 2021 08.

Article em En | MEDLINE | ID: mdl-33738833

Assuntos

Antiasmáticos; Asma; MicroRNAs; Antiasmáticos/uso terapêutico; Anticorpos Monoclonais Humanizados/uso terapêutico; Asma/tratamento farmacológico; Asma/genética; Eosinófilos; Humanos; MicroRNAs/genética; Esteroides/uso terapêutico

Palavras-chave

asthma; benralizumab; glucocorticoids; microRNAs; type 2 inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos / MicroRNAs Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Allergy Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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