The challenge of staying in shape: nuclear size matters.
Curr Genet
; 67(4): 605-612, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-33779777
ABSTRACT
Cellular organelles have unique morphology and the organelle size to cell size ratio is regulated. Nucleus is one of the most prominent, usually round in shape, organelle of a eukaryotic cell that occupies 8-10% of cellular volume. The shape and size of nucleus is known to undergo remodeling during processes such as cell growth, division and certain stresses. Regulation of protein and lipid distribution at the nuclear envelope is crucial for preserving the nuclear morphology and size. As size and morphology are interlinked, altering one influences the other. In this perspective, we discuss the relationship between size and shape regulation of the nucleus.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ciclo Celular
/
Núcleo Celular
/
Lipídeos
/
Membrana Nuclear
Limite:
Humans
Idioma:
En
Revista:
Curr Genet
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Índia