Your browser doesn't support javascript.
loading
Whole-Genome Analysis Surveillance of Influenza A Virus Resistance to Polymerase Complex Inhibitors in Eastern Spain from 2016 to 2019.
Mengual-Chuliá, Beatriz; Alonso-Cordero, Andrés; Cano, Laura; Mosquera, M Del Mar; de Molina, Patricia; Vendrell, Roser; Reyes-Prieto, Mariana; Jané, Mireia; Torner, Nuria; Martínez, Ana Isabel; Vila, Jordi; Díez-Domingo, Javier; Marcos, M Ángeles; López-Labrador, F Xavier.
Afiliação
  • Mengual-Chuliá B; Virology Laboratory, Genomics and Health Area, Centro Superior de Investigación en Salud Pública, FISABIO-Public Health, Generalitat Valenciana, Valencia, Spain.
  • Alonso-Cordero A; Virology Laboratory, Genomics and Health Area, Centro Superior de Investigación en Salud Pública, FISABIO-Public Health, Generalitat Valenciana, Valencia, Spain.
  • Cano L; Virology Laboratory, Genomics and Health Area, Centro Superior de Investigación en Salud Pública, FISABIO-Public Health, Generalitat Valenciana, Valencia, Spain.
  • Mosquera MDM; Microbiology Service, Center of Biomedical Diagnostics, Hospital Clínic, Universitat de Barcelona, Institute of Global Health, Barcelona, Spain.
  • de Molina P; Microbiology Service, Center of Biomedical Diagnostics, Hospital Clínic, Universitat de Barcelona, Institute of Global Health, Barcelona, Spain.
  • Vendrell R; Microbiology Service, Center of Biomedical Diagnostics, Hospital Clínic, Universitat de Barcelona, Institute of Global Health, Barcelona, Spain.
  • Reyes-Prieto M; Bioinformatics and Sequencing Service, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana, FISABIO-Public Health, Generalitat Valenciana, Valencia, Spain.
  • Jané M; Public Health Agency of Catalonia, Barcelona, Spain.
  • Torner N; Public Health Agency of Catalonia, Barcelona, Spain.
  • Martínez AI; Public Health Agency of Catalonia, Barcelona, Spain.
  • Vila J; Microbiology Service, Center of Biomedical Diagnostics, Hospital Clínic, Universitat de Barcelona, Institute of Global Health, Barcelona, Spain.
  • Díez-Domingo J; Vaccine Research Area, Centro Superior de Investigación en Salud Pública, FISABIO-Public Health, Generalitat Valenciana, Valencia, Spain.
  • Marcos MÁ; Microbiology Service, Center of Biomedical Diagnostics, Hospital Clínic, Universitat de Barcelona, Institute of Global Health, Barcelona, Spain.
  • López-Labrador FX; Virology Laboratory, Genomics and Health Area, Centro Superior de Investigación en Salud Pública, FISABIO-Public Health, Generalitat Valenciana, Valencia, Spain F.Xavier.Lopez@uv.es.
Antimicrob Agents Chemother ; 65(6)2021 05 18.
Article em En | MEDLINE | ID: mdl-33782005
ABSTRACT
Molecular surveillance by whole-genome sequencing was used to monitor the susceptibility of circulating influenza A viruses to three polymerase complex inhibitors. A total of 12 resistance substitutions were found among 285 genomes analyzed, but none were associated with high levels of resistance. Natural resistance to these influenza A antivirals is currently uncommon.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Influenza Humana Tipo de estudo: Screening_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Influenza Humana Tipo de estudo: Screening_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha