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The influence of abnormal pregnancies on fluorescence polarization of amniotic fluid lipids.
Barkai, G; Reichman, B; Modan, M; Goldman, B; Serr, D M; Mashiach, S.
Afiliação
  • Barkai G; Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Obstet Gynecol ; 72(1): 39-43, 1988 Jul.
Article em En | MEDLINE | ID: mdl-3380508
The fluorescence polarization of amniotic fluid, a measure of fetal lung maturity, was determined in 518 amniotic fluid samples obtained by amniocentesis. The subjects were divided into seven clinical groups: premature contractions, premature rupture of the membranes, pregnancy-induced hypertension, diabetes, intrauterine growth retardation, vaginal bleeding, and "other" for gestational-age groups of 30 weeks or less, 31-36 weeks, and 37 or more weeks. The proportion of mature values (fluorescence polarization 0.285 or lower) increased progressively from 12.5% at 27-28 weeks to 100% at 39-40 weeks. In the 31-36-week gestation group, the proportion of mature values in subjects with premature rupture of the membranes (84.6%) was significantly higher than in those with premature contractions (60%), severe pregnancy-induced hypertension (50%), mild pregnancy-induced hypertension (55.2%), diabetes class A (50%), insulin-dependent diabetes (60%), and other (63.5%). The mean +/- SD fluorescence polarization value was significantly lower in premature rupture of the membranes (0.256 +/- 0.030) than in premature contractions (0.274 +/- 0.032), mild and severe pregnancy-induced hypertension (0.280 +/- 0.027 and 0.280 +/- 0.035, respectively), and class A and insulin-dependent diabetes (0.285 +/- 0.018 and 0.277 +/- 0.030, respectively). The severity of pregnancy-induced hypertension and diabetes did not appear to influence either the fluorescence polarization value or the proportion of mature results. With the exception of a marked influence of premature rupture of the membranes, abnormal pregnancy conditions did not appear to have a significant effect on fluorescence polarization of amniotic fluid.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações na Gravidez / Líquido Amniótico / Lipídeos Limite: Female / Humans / Pregnancy Idioma: En Revista: Obstet Gynecol Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Israel
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações na Gravidez / Líquido Amniótico / Lipídeos Limite: Female / Humans / Pregnancy Idioma: En Revista: Obstet Gynecol Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Israel