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Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses.
Wilmes, Stephan; Jeffrey, Polly-Anne; Martinez-Fabregas, Jonathan; Hafer, Maximillian; Fyfe, Paul K; Pohler, Elizabeth; Gaggero, Silvia; López-García, Martín; Lythe, Grant; Taylor, Charles; Guerrier, Thomas; Launay, David; Mitra, Suman; Piehler, Jacob; Molina-París, Carmen; Moraga, Ignacio.
Afiliação
  • Wilmes S; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
  • Jeffrey PA; Department of Applied Mathematics, School of Mathematics, University of Leeds, Leeds, United Kingdom.
  • Martinez-Fabregas J; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
  • Hafer M; Department of Biology and Centre of Cellular Nanoanalytics, University of Osnabrück, Osnabrück, Germany.
  • Fyfe PK; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
  • Pohler E; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
  • Gaggero S; Université de Lille, INSERM UMR1277 CNRS UMR9020-CANTHER and Institut pour la Recherche sur le Cancer de Lille (IRCL), Lille, France.
  • López-García M; Department of Applied Mathematics, School of Mathematics, University of Leeds, Leeds, United Kingdom.
  • Lythe G; Department of Applied Mathematics, School of Mathematics, University of Leeds, Leeds, United Kingdom.
  • Taylor C; Department of Statistics, School of Mathematics, University of Leeds, Leeds, United Kingdom.
  • Guerrier T; Univ. Lille, Univ. LilleInserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, Lille, France.
  • Launay D; Univ. Lille, Univ. LilleInserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, Lille, France.
  • Mitra S; Université de Lille, INSERM UMR1277 CNRS UMR9020-CANTHER and Institut pour la Recherche sur le Cancer de Lille (IRCL), Lille, France.
  • Piehler J; Department of Biology and Centre of Cellular Nanoanalytics, University of Osnabrück, Osnabrück, Germany.
  • Molina-París C; Department of Applied Mathematics, School of Mathematics, University of Leeds, Leeds, United Kingdom.
  • Moraga I; T-6 Theoretical Division, Los Alamos National Laboratory, Los Alamos, United States.
Elife ; 102021 04 19.
Article em En | MEDLINE | ID: mdl-33871355
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-6 / Receptores de Interleucina / Células Th1 / Fator de Transcrição STAT1 / Fator de Transcrição STAT3 / Receptor gp130 de Citocina / Interleucina-27 Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-6 / Receptores de Interleucina / Células Th1 / Fator de Transcrição STAT1 / Fator de Transcrição STAT3 / Receptor gp130 de Citocina / Interleucina-27 Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido