Caspase inhibition prolongs inflammation by promoting a signaling complex with activated RIPK1.

Huang, Xinyue; Tan, Shuixia; Li, Yanxia; Cao, Shuangyi; Li, Xingyan; Pan, Heling; Shan, Bing; Qian, Lihui; Yuan, Junying

Huang, Xinyue; Tan, Shuixia; Li, Yanxia; Cao, Shuangyi; Li, Xingyan; Pan, Heling; Shan, Bing; Qian, Lihui; Yuan, Junying.

Afiliação

Huang X; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Tan S; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Li Y; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Cao S; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Li X; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Pan H; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Shan B; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Qian L; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.
Yuan J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, China.

J Cell Biol ; 220(6)2021 06 07.

Article em En | MEDLINE | ID: mdl-33914027

Assuntos

Caspase 8/química; Inibidores de Caspase/farmacologia; Citocinas/metabolismo; Imunidade Inata/efeitos dos fármacos; Inflamação/patologia; Proteína Serina-Treonina Quinases de Interação com Receptores/metabolismo; Animais; Caspase 8/genética; Caspase 8/metabolismo; Humanos; Inflamação/tratamento farmacológico; Inflamação/imunologia; Inflamação/metabolismo; Camundongos; NF-kappa B/genética; NF-kappa B/metabolismo; Fosforilação; Proteína Serina-Treonina Quinases de Interação com Receptores/genética; Receptores Tipo I de Fatores de Necrose Tumoral/genética; Receptores Tipo I de Fatores de Necrose Tumoral/metabolismo; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Caspase 8 / Proteína Serina-Treonina Quinases de Interação com Receptores / Inibidores de Caspase / Imunidade Inata / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Cell Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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